A randomized clinical pharmacokinetic trial of Tenofovir in blood, plasma and urine in adults with perfect, moderate and low PrEP adherence: the TARGET study

BACKGROUND: Tenofovir disoproxil fumarate (TDF) is key component of pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) for HIV, but existing tools to monitor drug adherence are often inaccurate. Detection of tenofovir (TFV) in accessible biological samples, such as fingerprick blood, u...

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Опубликовано в: :BMC Infect Dis
Главные авторы: Cressey, Tim R., Siriprakaisil, Oraphan, Klinbuayaem, Virat, Quame-Amaglo, Justice, Kubiak, Rachel W., Sukrakanchana, Pra-ornsuda, Than-in-at, Kanchana, Baeten, Jared, Sirirungsi, Wasna, Cressey, Ratchada, Drain, Paul K.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Study Protocol
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513124/
https://ncbi.nlm.nih.gov/pubmed/28705153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2593-4
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