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A randomized clinical pharmacokinetic trial of Tenofovir in blood, plasma and urine in adults with perfect, moderate and low PrEP adherence: the TARGET study

BACKGROUND: Tenofovir disoproxil fumarate (TDF) is key component of pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) for HIV, but existing tools to monitor drug adherence are often inaccurate. Detection of tenofovir (TFV) in accessible biological samples, such as fingerprick blood, u...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Cressey, Tim R., Siriprakaisil, Oraphan, Klinbuayaem, Virat, Quame-Amaglo, Justice, Kubiak, Rachel W., Sukrakanchana, Pra-ornsuda, Than-in-at, Kanchana, Baeten, Jared, Sirirungsi, Wasna, Cressey, Ratchada, Drain, Paul K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513124/
https://ncbi.nlm.nih.gov/pubmed/28705153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2593-4
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