Validation of a Urine Tenofovir Immunoassay for Adherence Monitoring to PrEP and ART and Establishing the Cut-Off for a Point-of-Care Test

BACKGROUND: Current pharmacologic adherence monitoring for antiretrovirals involves expensive, labor-intensive liquid-chromatography/tandem-mass-spectrometry (LC-MS/MS)-based methods. Antibody-based assays can monitor and support adherence in real-time. We developed a tenofovir (TFV)-based immunoass...

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Vydáno v:J Acquir Immune Defic Syndr
Hlavní autoři: Gandhi, Monica, Bacchetti, Peter, SpinelliI, Matthew A., Okochi, Hideaki, Baeten, Jared M., Siriprakaisil, Oraphan, Klinbuayaem, Virat, Rodrigues, Warren C., Wang, Guohang, Vincent, Michael, Cressey, Tim R., Drain, Paul K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456396/
https://ncbi.nlm.nih.gov/pubmed/30664078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001971
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