Plasma and Intracellular Pharmacokinetics of Tenofovir Disoproxil Fumarate 300 mg Every 48 Hours vs 150 mg Once Daily in HIV-Infected Adults With Moderate Renal Function Impairment

Background. The approved tenofovir disoproxil fumarate (TDF) dose of 300 mg every 48 hours for adults with moderate renal impairment is often confusing and inconvenient. Using a new TDF formulation, we compared the pharmacokinetics of the standard dose with a dose of 150 mg once daily in HIV-infecte...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Cressey, Tim R., Avihingsanon, Anchalee, Halue, Guttiga, Leenasirimakul, Prattana, Sukrakanchana, Pra-ornsuda, Tawon, Yardpiroon, Jaisieng, Nirattiya, Jourdain, Gonzague, Podany, Anthony T., Fletcher, Courtney V., Klinbuayaem, Virat, Bowonwatanuwong, Chureeratana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
HIV/AIDS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607735/
https://ncbi.nlm.nih.gov/pubmed/25921689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ346
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