Endothelial-to-osteoblast conversion generates osteoblastic metastasis of prostate cancer

Prostate cancer (PCa) bone metastasis is frequently associated with bone-forming lesions, but the source of the osteoblastic lesions remains unclear. We show that the tumor-induced bone derives partly from tumor-associated endothelial cells that have undergone endothelial-to-osteoblast (EC-to-OSB) c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Dev Cell
Päätekijät: Lin, Song-Chang, Lee, Yu-Chen, Yu, Guoyu, Cheng, Chien-Jui, Zhou, Xin, Chu, Khoi, Murshed, Monzur, Le, Nhat-Tu, Baseler, Laura, Abe, Jun-ichi, Fujiwara, Keigi, deCrombrugghe, Benoit, Logothetis, Christopher J., Gallick, Gary E., Yu-Lee, Li-Yuan, Maity, Sankar N., Lin, Sue-Hwa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512590/
https://ncbi.nlm.nih.gov/pubmed/28586644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.05.005
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