Multiple pathways coordinating reprogramming of endothelial cells into osteoblasts by BMP4

Cell type transition occurs during normal development and under pathological conditions. In prostate cancer bone metastasis, prostate cancer-secreted BMP4 induces endothelial cell-to-osteoblast (EC-to-OSB) transition. Such tumor-induced stromal reprogramming supports prostate cancer progression. We...

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Publicado no:iScience
Main Authors: Yu, Guoyu, Shen, Pengfei, Lee, Yu-Chen, Pan, Jing, Song, Jian H., Pan, Tianhong, Lin, Song-Chang, Liang, Xin, Wang, Guocan, Panaretakis, Theocharis, Logothetis, Christopher J., Gallick, Gary E., Yu-Lee, Li-Yuan, Lin, Sue-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086028/
https://ncbi.nlm.nih.gov/pubmed/33981975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102388
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