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The Src Family Kinase/Abl Inhibitor Dasatinib Suppresses Proliferation and Enhances Differentiation of Osteoblasts

Dasatinib, a dual Src family kinase and Abl inhibitor, is being tested clinically for the treatment of prostate cancer bone metastasis. Bidirectional interactions between osteoblasts and prostate cancer cells are critical in the progression of prostate cancer in bone, but the effect of dasatinib on...

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書誌詳細
主要な著者: Lee, Yu-Chen, Huang, Chih-Fen, Murshed, Monzur, Chu, Khoi, Araujo, John C., Ye, Xiangcang, deCrombrugghe, Benoit, Yu-Lee, Li-Yuan, Gallick, Gary E., Lin, Sue-Hwa
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921959/
https://ncbi.nlm.nih.gov/pubmed/20228840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.73
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