The Src Family Kinase/Abl Inhibitor Dasatinib Suppresses Proliferation and Enhances Differentiation of Osteoblasts

Dasatinib, a dual Src family kinase and Abl inhibitor, is being tested clinically for the treatment of prostate cancer bone metastasis. Bidirectional interactions between osteoblasts and prostate cancer cells are critical in the progression of prostate cancer in bone, but the effect of dasatinib on...

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Detalhes bibliográficos
Main Authors: Lee, Yu-Chen, Huang, Chih-Fen, Murshed, Monzur, Chu, Khoi, Araujo, John C., Ye, Xiangcang, deCrombrugghe, Benoit, Yu-Lee, Li-Yuan, Gallick, Gary E., Lin, Sue-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921959/
https://ncbi.nlm.nih.gov/pubmed/20228840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.73
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