Antitumor Effect of KX-01 through Inhibiting Src Family Kinases and Mitosis

PURPOSE: KX-01 is a novel dual inhibitor of Src and tubulin. Unlike previous Src inhibitors that failed to show clinical benefit during treatment of breast cancer, KX-01 can potentially overcome the therapeutic limitations of current Src inhibitors through inhibition of both Src and tubulin. The pre...

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Publicado no:Cancer Res Treat
Main Authors: Kim, Seongyeong, Min, Ahrum, Lee, Kyung-Hun, Yang, Yaewon, Kim, Tae-Yong, Lim, Jee Min, Park, So Jung, Nam, Hyun-Jin, Kim, Jung Eun, Song, Sang-Hyun, Han, Sae-Won, Oh, Do-Youn, Kim, Jee Hyun, Kim, Tae-You, Hangauer, David, Lau, Johnson Yiu-Nam, Im, Kyongok, Lee, Dong Soon, Bang, Yung-Jue, Im, Seock-Ah
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Cancer Association 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512373/
https://ncbi.nlm.nih.gov/pubmed/27737538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2016.168
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