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Three Pyrimidine Decarboxylations in the Absence of a Catalyst
The epigenetic modification of DNA by 5-methylation of cytosine residues can be reversed by the action of the TET family of dioxygenases that oxidize the methyl group to produce 5-carboxycytosine (5caC), which can be converted to cytosine in a final decarboxylation step. Likewise, 5-carboxyuracil (5...
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| Publicat a: | Biochemistry |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512268/ https://ncbi.nlm.nih.gov/pubmed/28225618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00055 |
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