A Map of the Arenavirus Nucleoprotein-Host Protein Interactome Reveals that Junín Virus Selectively Impairs the Antiviral Activity of Double-Stranded RNA-Activated Protein Kinase (PKR)

Arenaviruses are enveloped negative-strand RNA viruses that cause significant human disease. These viruses encode only four proteins to accomplish the viral life cycle, so each arenavirus protein likely plays unappreciated accessory roles during infection. Here we used immunoprecipitation and mass s...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: King, Benjamin R., Hershkowitz, Dylan, Eisenhauer, Philip L., Weir, Marion E., Ziegler, Christopher M., Russo, Joanne, Bruce, Emily A., Ballif, Bryan A., Botten, Jason
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512243/
https://ncbi.nlm.nih.gov/pubmed/28539447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00763-17
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