A Map of the Arenavirus Nucleoprotein-Host Protein Interactome Reveals that Junín Virus Selectively Impairs the Antiviral Activity of Double-Stranded RNA-Activated Protein Kinase (PKR)

Arenaviruses are enveloped negative-strand RNA viruses that cause significant human disease. These viruses encode only four proteins to accomplish the viral life cycle, so each arenavirus protein likely plays unappreciated accessory roles during infection. Here we used immunoprecipitation and mass s...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: King, Benjamin R., Hershkowitz, Dylan, Eisenhauer, Philip L., Weir, Marion E., Ziegler, Christopher M., Russo, Joanne, Bruce, Emily A., Ballif, Bryan A., Botten, Jason
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512243/
https://ncbi.nlm.nih.gov/pubmed/28539447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00763-17
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