Epstein-Barr Virus Rta-Mediated Accumulation of DNA Methylation Interferes with CTCF Binding in both Host and Viral Genomes

Rta, an Epstein-Barr virus (EBV) immediate-early protein, reactivates viral lytic replication that is closely associated with tumorigenesis. In previous studies, we demonstrated that in epithelial cells Rta efficiently induced cellular senescence, which is an irreversible G(1) arrest likely to provi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Chen, Yen-Ju, Chen, Yu-Lian, Chang, Yao, Wu, Chung-Chun, Ko, Ying-Chieh, Tsao, Sai Wah, Chen, Jen-Yang, Lin, Su-Fang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Genome Replication and Regulation of Viral Gene Expression
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512236/
https://ncbi.nlm.nih.gov/pubmed/28490592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00736-17
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