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Epstein-Barr Virus LF2 Protein Regulates Viral Replication by Altering Rta Subcellular Localization

The switch from Epstein-Barr virus (EBV) latent infection to lytic replication is governed by two viral transactivators, Zta and Rta. We previously reported that the EBV protein LF2 binds Rta, inhibits Rta promoter activation, and blocks EBV replication in cells. In addition, LF2 induces SUMO2/3 mod...

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Detalhes bibliográficos
Main Authors: Heilmann, Andreas M. F., Calderwood, Michael A., Johannsen, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937793/
https://ncbi.nlm.nih.gov/pubmed/20631124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00573-10
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