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Epstein-Barr Virus LF2 Protein Regulates Viral Replication by Altering Rta Subcellular Localization

The switch from Epstein-Barr virus (EBV) latent infection to lytic replication is governed by two viral transactivators, Zta and Rta. We previously reported that the EBV protein LF2 binds Rta, inhibits Rta promoter activation, and blocks EBV replication in cells. In addition, LF2 induces SUMO2/3 mod...

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Hlavní autoři: Heilmann, Andreas M. F., Calderwood, Michael A., Johannsen, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937793/
https://ncbi.nlm.nih.gov/pubmed/20631124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00573-10
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