Antileishmanial activity and tubulin polymerization inhibition of podophyllotoxin derivatives on Leishmania infantum

Leishmania microtubules play an important role not only in cell division, but also in keeping the shape of the parasite and motility of its free-living stages. Microtubules result from the self-assembly of alpha and beta tubulins, two phylogenetically conserved and very abundant eukaryotic proteins...

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Detalles Bibliográficos
Publicado en:Int J Parasitol Drugs Drug Resist
Main Authors: Escudero-Martínez, José Miguel, Pérez-Pertejo, Yolanda, Reguera, Rosa M., Castro, María Ángeles, Rojo, María Victoria, Santiago, Carolina, Abad, Andrés, García, Pablo Anselmo, López-Pérez, José Luis, San Feliciano, Arturo, Balaña-Fouce, Rafael
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512185/
https://ncbi.nlm.nih.gov/pubmed/28719882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.06.003
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