Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis

BACKGROUND & AIMS: There is growing interest in the use of bone marrow cells to treat liver fibrosis, however, little is known about their antifibrotic efficacy or the identity of their effector cell(s). Sphingosine-1-phosphate (S1P) mediates egress of immune cells from the lymphoid organs into...

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Publicado en:Gastroenterology
Autores principales: King, Andrew, Houlihan, Diarmaid D., Kavanagh, Dean, Haldar, Debashis, Luu, Nguyet, Owen, Andrew, Suresh, Shankar, Than, Nwe Ni, Reynolds, Gary, Penny, Jasmine, Sumption, Henry, Ramachandran, Prakash, Henderson, Neil C., Kalia, Neena, Frampton, Jon, Adams, David H., Newsome, Philip N.
Formato: Artigo
Lenguaje:Inglês
Publicado: W.B. Saunders 2017
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511862/
https://ncbi.nlm.nih.gov/pubmed/28363640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.03.022
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