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Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis

BACKGROUND & AIMS: There is growing interest in the use of bone marrow cells to treat liver fibrosis, however, little is known about their antifibrotic efficacy or the identity of their effector cell(s). Sphingosine-1-phosphate (S1P) mediates egress of immune cells from the lymphoid organs into...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: King, Andrew, Houlihan, Diarmaid D., Kavanagh, Dean, Haldar, Debashis, Luu, Nguyet, Owen, Andrew, Suresh, Shankar, Than, Nwe Ni, Reynolds, Gary, Penny, Jasmine, Sumption, Henry, Ramachandran, Prakash, Henderson, Neil C., Kalia, Neena, Frampton, Jon, Adams, David H., Newsome, Philip N.
Formato: Artigo
Idioma:Inglês
Publicado em: W.B. Saunders 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511862/
https://ncbi.nlm.nih.gov/pubmed/28363640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.03.022
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