Genome-Wide Linkage Analysis of Large Multiple Multigenerational Families Identifies Novel Genetic Loci for Coronary Artery Disease

Coronary artery disease (CAD) is the leading cause of death, and genetic factors contribute significantly to risk of CAD. This study aims to identify new CAD genetic loci through a large-scale linkage analysis of 24 large and multigenerational families with 433 family members (GeneQuest II). All fam...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guo, Yang, Wang, Fan, Li, Lin, Gao, Hanxiang, Arckacki, Stephen, Wang, Isabel Z., Barnard, John, Ellis, Stephen, Hubbard, Carlos, Topol, Eric J., Chen, Qiuyun, Wang, Qing K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511258/
https://ncbi.nlm.nih.gov/pubmed/28710368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05381-2
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