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Genome-Wide Linkage Analysis of Quantitative Biomarker Traits of Osteoarthritis in a Large Multigenerational Extended Family

OBJECTIVE: The genetic contributions to the multifactorial disorder osteoarthritis (OA) have been increasingly recognized. Our goal was to use OA-related biomarkers of severity and disease burden as quantitative traits to identify genetic susceptibility loci for OA. METHODS: In a large multigenerati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Hsiang-Cheng, Kraus, Virginia Byers, Li, Yi-Ju, Nelson, Sarah, Haynes, Carol, Johnson, Jessica, Stabler, Thomas, Hauser, Elizabeth R., Gregory, Simon G., Kraus, William E., Shah, Svati H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684272/
https://ncbi.nlm.nih.gov/pubmed/20187133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27288
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