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Genome-Wide Linkage Analysis of Quantitative Biomarker Traits of Osteoarthritis in a Large Multigenerational Extended Family

OBJECTIVE: The genetic contributions to the multifactorial disorder osteoarthritis (OA) have been increasingly recognized. Our goal was to use OA-related biomarkers of severity and disease burden as quantitative traits to identify genetic susceptibility loci for OA. METHODS: In a large multigenerati...

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Hlavní autoři: Chen, Hsiang-Cheng, Kraus, Virginia Byers, Li, Yi-Ju, Nelson, Sarah, Haynes, Carol, Johnson, Jessica, Stabler, Thomas, Hauser, Elizabeth R., Gregory, Simon G., Kraus, William E., Shah, Svati H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684272/
https://ncbi.nlm.nih.gov/pubmed/20187133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27288
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