Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc(Min/+) mice

Increased expression of Interleukin (IL)-33 has been detected in intestinal samples of patients with ulcerative colitis, a condition associated with increased risk for colon cancer, but its role in the development of colorectal cancer has yet to be fully examined. Here, we investigated the role of e...

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Udgivet i:Sci Rep
Main Authors: He, Zhengxiang, Chen, Lili, Souto, Fabricio O., Canasto-Chibuque, Claudia, Bongers, Gerold, Deshpande, Madhura, Harpaz, Noam, Ko, Huaibin M., Kelley, Kevin, Furtado, Glaucia C., Lira, Sergio A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511216/
https://ncbi.nlm.nih.gov/pubmed/28710436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05716-z
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