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Mutant Ataxin-1 Inhibits Neural Progenitor Cell Proliferation in SCA1

Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease caused by the expansion of a polyglutamine (Q) repeat tract in the protein ataxin-1 (ATXN1). Beginning as a cerebellar ataxic disorder, SCA1 progresses to involve the cerebral cortex, hippocampus, and brainstem....

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Bibliografski detalji
Izdano u:Cerebellum
Glavni autori: Cvetanovic, Marija, Hu, Yuan-Shih, Opal, Puneet
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510931/
https://ncbi.nlm.nih.gov/pubmed/27306906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-016-0794-9
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