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Mutant Ataxin-1 Inhibits Neural Progenitor Cell Proliferation in SCA1
Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease caused by the expansion of a polyglutamine (Q) repeat tract in the protein ataxin-1 (ATXN1). Beginning as a cerebellar ataxic disorder, SCA1 progresses to involve the cerebral cortex, hippocampus, and brainstem....
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| Publicado no: | Cerebellum |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5510931/ https://ncbi.nlm.nih.gov/pubmed/27306906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-016-0794-9 |
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