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BinomiRare: a robust test of the association of a rare-variant with a disease for pooled and meta-analysis, with application to the HCHS/SOL
Most regression-based tests of the association between a low-count variant and a binary outcome do not protect type 1 error, especially when tests are rejected based on a very low significance threshold. Noted exception is the Firth test. However, it was recently shown that in meta-analyzing multipl...
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| Argitaratua izan da: | Genet Epidemiol |
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| Egile nagusia: | |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5510891/ https://ncbi.nlm.nih.gov/pubmed/28393384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22044 |
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