Meta-analysis of genome-wide association studies with correlated individuals: application to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Investigators often meta-analyze multiple genome-wide association studies (GWASs) to increase the power to detect associations of single nucleotide polymorphisms (SNPs) with a trait. Meta-analysis is also performed within a single cohort that is stratified by, e.g., sex or ancestry group. Having cor...

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Veröffentlicht in:Genet Epidemiol
Hauptverfasser: Sofer, Tamar, Shaffer, John R., Graff, Misa, Qi, Qibin, Stilp, Adrienne M., Gogarten, Stephanie M., North, Kari E., Isasi, Carmen R., Laurie, Cathy C., Szpiro, Adam A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981554/
https://ncbi.nlm.nih.gov/pubmed/27256683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21981
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