Improved imputation accuracy in Hispanic/Latino populations with larger and more diverse reference panels: applications in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Imputation is commonly used in genome-wide association studies to expand the set of genetic variants available for analysis. Larger and more diverse reference panels, such as the final Phase 3 of the 1000 Genomes Project, hold promise for improving imputation accuracy in genetically diverse populati...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Nelson, Sarah C., Stilp, Adrienne M., Papanicolaou, George J., Taylor, Kent D., Rotter, Jerome I., Thornton, Timothy A., Laurie, Cathy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179925/
https://ncbi.nlm.nih.gov/pubmed/27346520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw174
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