Inhibition of the apelin/apelin receptor axis decreases cholangiocarcinoma growth

PURPOSE: Cholangiocarcinoma (CCA) is a malignancy of the biliary epithelium that is associated with low five-year survival. The apelin receptor (APLNR), which is activated by the apelin peptide, has not been studied in CCA. The purpose of this study is to determine if inhibition of the apelin/APLNR...

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Bibliographic Details
Published in:Cancer Lett
Main Authors: Hall, Chad, Ehrlich, Laurent, Venter, Julie, O’Brien, April, White, Tori, Zhou, Tianhao, Dang, Tien, Meng, Fanyin, Invernizzi, Pietro, Bernuzzi, Francesca, Alpini, Gianfranco, Lairmore, Terry C., Glaser, Shannon
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510601/
https://ncbi.nlm.nih.gov/pubmed/27894959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.11.025
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