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Inhibition of microRNA-24 increases liver fibrosis by enhanced menin expression in Mdr2(−/−) mice

BACKGROUND: Liver transplantation remains the primary treatment for primary sclerosing cholangitis (PSC). Mdr2(−/−) mice provide a reliable in vivo model of PSC and develop characteristic biliary inflammation and fibrosis. We tested the hypothesis that the tumor suppressor protein menin is implicate...

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Detalhes bibliográficos
Publicado no:J Surg Res
Main Authors: Hall, Chad, Ehrlich, Laurent, Meng, Fanyin, Invernizzi, Pietro, Bernuzzi, Francesca, Lairmore, Terry C., Alpini, Gianfranco, Glaser, Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760243/
https://ncbi.nlm.nih.gov/pubmed/28602220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2017.05.020
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