α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile Duct-Ligated Mice

α7-nAChR is a nicotinic acetylcholine receptor [specifically expressed on hepatic stellate cells (HSCs), Kupffer cells, and cholangiocytes] that regulates inflammation and apoptosis in the liver. Thus, targeting α7-nAChR may be therapeutic in biliary diseases. Bile duct ligation (BDL) was performed...

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Detalhes bibliográficos
Publicado no:Gene Expr
Main Authors: Ehrlich, Laurent, O’Brien, April, Hall, Chad, White, Tori, Chen, Lixian, Wu, Nan, Venter, Julie, Scrushy, Marinda, Mubarak, Muhammad, Meng, Fanyin, Dostal, David, Wu, Chaodong, Lairmore, Terry C., Alpini, Gianfranco, Glaser, Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190116/
https://ncbi.nlm.nih.gov/pubmed/29580318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221618X15216453076707
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