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Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31

Lecithin:cholesterol acyltransferase (LCAT) catalyzes plasma cholesteryl ester formation and is defective in familial lecithin:cholesterol acyltransferase deficiency (FLD), an autosomal recessive disorder characterized by low high-density lipoprotein, anemia, and renal disease. This study aimed to i...

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Podrobná bibliografie
Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Freeman, Lita A., Demosky, Stephen J., Konaklieva, Monika, Kuskovsky, Rostislav, Aponte, Angel, Ossoli, Alice F., Gordon, Scott M., Koby, Ross F., Manthei, Kelly A., Shen, Min, Vaisman, Boris L., Shamburek, Robert D., Jadhav, Ajit, Calabresi, Laura, Gucek, Marjan, Tesmer, John J.G., Levine, Rodney L., Remaley, Alan T.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510151/
https://ncbi.nlm.nih.gov/pubmed/28576974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.240457
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