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A bosentan pharmacokinetic study to investigate dosing regimens in paediatric patients with pulmonary arterial hypertension: FUTURE‐3
AIM: The aim of the present study was to investigate whether increasing the bosentan dosing frequency from 2 mg kg(–1) twice daily (b.i.d.) to 2 mg kg(–1) three times daily (t.i.d.) in children with pulmonary arterial hypertension (PAH) (from ≥3 months to <12 years of age) would increase exposure...
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| Опубликовано в: : | Br J Clin Pharmacol |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5510076/ https://ncbi.nlm.nih.gov/pubmed/28213957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13267 |
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