Pharmacokinetic and clinical profile of a novel formulation of bosentan in children with pulmonary arterial hypertension: the FUTURE-1 study

AIM: To show equivalent bosentan exposure in paediatric patients with pulmonary arterial hypertension (PAH) when compared with a cohort of historical controls of adult PAH patients using a newly developed paediatric formulation. METHODS: Thirty-six paediatric PAH patients were enrolled in this multi...

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Detalhes bibliográficos
Main Authors: Beghetti, Maurice, Haworth, Sheila G, Bonnet, Damien, Barst, Robyn J, Acar, Philippe, Fraisse, Alain, Ivy, Dunbar D, Jais, Xavier, Schulze-Neick, Ingram, Galiè, Nazzareno, Morganti, Adele, Dingemanse, Jasper, Kusic-Pajic, Andjela, Berger, Rolf M F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Paediatric Clinical Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805863/
https://ncbi.nlm.nih.gov/pubmed/20002090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03532.x
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