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Design, preparation, and selection of DNA-encoded dynamic libraries
We report a method for the preparation and selection of DNA-encoded dynamic libraries (DEDLs). The library is composed of two sets of DNA-linked small molecules that are under dynamic exchange through DNA hybridization. Addition of the protein target shifted the equilibrium, favouring the assembly o...
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| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5510007/ https://ncbi.nlm.nih.gov/pubmed/28757982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02467f |
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