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The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells

KEY POINTS: The angiotensin II receptor type 1b (AT(1)R(b)) is the primary sensor of intraluminal pressure in cerebral arteries. Pressure or membrane‐stretch induced stimulation of AT(1)R(b) activates the TRPM4 channel and results in inward transient cation currents that depolarize smooth muscle cel...

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Bibliografske podrobnosti
izdano v:J Physiol
Main Authors: Pires, Paulo W., Ko, Eun‐A., Pritchard, Harry A.T., Rudokas, Michael, Yamasaki, Evan, Earley, Scott
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509855/
https://ncbi.nlm.nih.gov/pubmed/28475214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274310
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