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DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia

The morphogenic factor Sonic hedgehog (Shh) signals through the primary cilium, which relies on intraflagellar transport to maintain its structural integrity and function. However, the process by which protein and lipid cargos are delivered to the primary cilium from their sites of synthesis still r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ding, Jie, Shao, Lei, Yao, Yixing, Tong, Xin, Liu, Huaize, Yue, Shen, Xie, Lu, Cheng, Steven Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509727/
https://ncbi.nlm.nih.gov/pubmed/28706295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05680-8
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