Stimulation of Synaptoneurosome Glutamate Release by Monomeric and Fibrillated α-Synuclein

The α-synuclein protein exists in vivo in a variety of covalently modified and aggregated forms associated with Parkinson’s disease (PD) pathology. However, the specific proteoform structures involved with neuropathological disease mechanisms are not clearly defined. Since α-synuclein plays a role i...

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Veröffentlicht in:J Neurosci Res
Hauptverfasser: Sarafian, Theodore A., Littlejohn, Kaitlyn, Yuan, Sarah, Fernandez, Charlene, Cilluffo, Marianne, Koo, Bon-Kyung, Whitelegge, Julian P., Watson, Joseph B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509520/
https://ncbi.nlm.nih.gov/pubmed/28117497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.24024
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