Constitutive increases in corticotropin releasing factor and fatty acid amide hydrolase drive an anxious phenotype

BACKGROUND: Corticotropin-releasing factor (CRF) mediates anxiogenic responses by activating CRF(1) receptors in limbic brain regions. Anxiety is further modulated by the endogenous cannabinoid (eCB) system that attenuates the synaptic effects of stress. In the amygdala, acute stress activates the e...

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Publicat a:Biol Psychiatry
Autors principals: Natividad, Luis A., Buczynski, Matthew W., Herman, Melissa A., Kirson, Dean, Oleata, Christopher S., Irimia, Cristina, Polis, Ilham, Ciccocioppo, Roberto, Roberto, Marisa, Parsons, Loren H.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509512/
https://ncbi.nlm.nih.gov/pubmed/28209423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.01.005
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