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Intestinal calcium and bile salts facilitate germination of Clostridium difficile spores

Clostridium difficile (C. difficile) is an anaerobic gram-positive pathogen that is the leading cause of nosocomial bacterial infection globally. C. difficile infection (CDI) typically occurs after ingestion of infectious spores by a patient that has been treated with broad-spectrum antibiotics. Whi...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Kochan, Travis J., Somers, Madeline J., Kaiser, Alyssa M., Shoshiev, Michelle S., Hagan, Ada K., Hastie, Jessica L., Giordano, Nicole P., Smith, Ashley D., Schubert, Alyxandria M., Carlson, Paul E., Hanna, Philip C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509370/
https://ncbi.nlm.nih.gov/pubmed/28704538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006443
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