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Metabolism of Bile Salts in Mice Influences Spore Germination in Clostridium difficile

Clostridium difficile, a spore-forming bacterium, causes antibiotic-associated diarrhea. In order to produce toxins and cause disease, C. difficile spores must germinate and grow out as vegetative cells in the host. Although a few compounds capable of germinating C. difficile spores in vitro have be...

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Bibliografiske detaljer
Main Authors: Giel, Jennifer L., Sorg, Joseph A., Sonenshein, Abraham L., Zhu, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806926/
https://ncbi.nlm.nih.gov/pubmed/20090901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008740
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