Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing

It has been suggested that chemoresistance of chondrosarcoma (CHS), the cartilage tumor, is caused by the phenotypic microenvironmental features of the tumor tissue, mainly the chondrogenic extracellular matrix (ECM), and hypoxia. We developed and characterized a multicellular tumor spheroid (MCTS)...

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Pubblicato in:PLoS One
Autori principali: Voissiere, Aurélien, Jouberton, Elodie, Maubert, Elise, Degoul, Françoise, Peyrode, Caroline, Chezal, Jean-Michel, Miot-Noirault, Élisabeth
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509331/
https://ncbi.nlm.nih.gov/pubmed/28704566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181340
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