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Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing

It has been suggested that chemoresistance of chondrosarcoma (CHS), the cartilage tumor, is caused by the phenotypic microenvironmental features of the tumor tissue, mainly the chondrogenic extracellular matrix (ECM), and hypoxia. We developed and characterized a multicellular tumor spheroid (MCTS)...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Voissiere, Aurélien, Jouberton, Elodie, Maubert, Elise, Degoul, Françoise, Peyrode, Caroline, Chezal, Jean-Michel, Miot-Noirault, Élisabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509331/
https://ncbi.nlm.nih.gov/pubmed/28704566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181340
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