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Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing
It has been suggested that chemoresistance of chondrosarcoma (CHS), the cartilage tumor, is caused by the phenotypic microenvironmental features of the tumor tissue, mainly the chondrogenic extracellular matrix (ECM), and hypoxia. We developed and characterized a multicellular tumor spheroid (MCTS)...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5509331/ https://ncbi.nlm.nih.gov/pubmed/28704566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181340 |
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