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Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing

It has been suggested that chemoresistance of chondrosarcoma (CHS), the cartilage tumor, is caused by the phenotypic microenvironmental features of the tumor tissue, mainly the chondrogenic extracellular matrix (ECM), and hypoxia. We developed and characterized a multicellular tumor spheroid (MCTS)...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Voissiere, Aurélien, Jouberton, Elodie, Maubert, Elise, Degoul, Françoise, Peyrode, Caroline, Chezal, Jean-Michel, Miot-Noirault, Élisabeth
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509331/
https://ncbi.nlm.nih.gov/pubmed/28704566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181340
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