Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing

It has been suggested that chemoresistance of chondrosarcoma (CHS), the cartilage tumor, is caused by the phenotypic microenvironmental features of the tumor tissue, mainly the chondrogenic extracellular matrix (ECM), and hypoxia. We developed and characterized a multicellular tumor spheroid (MCTS)...

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Опубликовано в: :PLoS One
Главные авторы: Voissiere, Aurélien, Jouberton, Elodie, Maubert, Elise, Degoul, Françoise, Peyrode, Caroline, Chezal, Jean-Michel, Miot-Noirault, Élisabeth
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509331/
https://ncbi.nlm.nih.gov/pubmed/28704566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181340
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