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Structure and dynamics of a 197 base-pair nucleosome in complex with linker histone H1

Linker histones associate with nucleosomes to promote the formation of higher-order chromatin structure, but the underlying molecular details are unclear. We investigated the structure of a 197 base-pair nucleosome bearing symmetric 25 base-pair linker DNA arms in complex with vertebrate linker hist...

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Pubblicato in:Mol Cell
Autori principali: Bednar, Jan, Garcia-Saez, Isabel, Boopathi, Ramachandran, Cutter, Amber R., Papai, Gabor, Reymer, Anna, Syed, Sajad H., Lone, Imtiaz Nisar, Tonchev, Ognyan, Crucifix, Corinne, Menoni, Hervé, Papin, Christophe, Skoufias, Dimitrios A., Kurumizaka, Hitoshi, Lavery, Richard, Hamiche, Ali, Hayes, Jeffrey J., Schultz, Patrick, Angelov, Dimitar, Petosa, Carlo, Dimitrov, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508712/
https://ncbi.nlm.nih.gov/pubmed/28475873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.04.012
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