Differential signaling networks of Bcr–Abl p210 and p190 kinases in leukemia cells defined by functional proteomics

The two major isoforms of the oncogenic Bcr–Abl tyrosine kinase, p210 and p190, are expressed upon the Philadelphia chromosome translocation. p210 is the hallmark of chronic myelogenous leukemia, whereas p190 occurs in the majority of B-cell acute lymphoblastic leukemia. Differences in protein inter...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Leukemia
Hoofdauteurs: Reckel, S, Hamelin, R, Georgeon, S, Armand, F, Jolliet, Q, Chiappe, D, Moniatte, M, Hantschel, O
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
Onderwerpen:
Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508078/
https://ncbi.nlm.nih.gov/pubmed/28111465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.36
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items