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Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation

Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis. In this study, we treated bone marrow cells (BMCs) from mice with purified α-toxin and found that TER119(+) erythroblasts were greatly decr...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Takagishi, Teruhisa, Takehara, Masaya, Seike, Soshi, Miyamoto, Kazuaki, Kobayashi, Keiko, Nagahama, Masahiro
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507896/
https://ncbi.nlm.nih.gov/pubmed/28701754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05567-8
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