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Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation

Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis. In this study, we treated bone marrow cells (BMCs) from mice with purified α-toxin and found that TER119(+) erythroblasts were greatly decr...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Takagishi, Teruhisa, Takehara, Masaya, Seike, Soshi, Miyamoto, Kazuaki, Kobayashi, Keiko, Nagahama, Masahiro
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507896/
https://ncbi.nlm.nih.gov/pubmed/28701754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05567-8
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