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Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation

Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis. In this study, we treated bone marrow cells (BMCs) from mice with purified α-toxin and found that TER119(+) erythroblasts were greatly decr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takagishi, Teruhisa, Takehara, Masaya, Seike, Soshi, Miyamoto, Kazuaki, Kobayashi, Keiko, Nagahama, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507896/
https://ncbi.nlm.nih.gov/pubmed/28701754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05567-8
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