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Divergence of cAMP signaling pathways mediating augmented nucleotide excision repair and pigment induction in melanocytes
Loss-of-function melanocortin 1 receptor (MC1R) polymorphisms are common in UV-sensitive fair-skinned individuals and are associated with blunted cAMP second messenger signaling and higher lifetime risk of melanoma because of diminished ability of melanocytes to cope with UV damage. cAMP signaling p...
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| Опубликовано в: : | Exp Dermatol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507718/ https://ncbi.nlm.nih.gov/pubmed/28094871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13291 |
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