Divergence of cAMP signaling pathways mediating augmented nucleotide excision repair and pigment induction in melanocytes

Loss-of-function melanocortin 1 receptor (MC1R) polymorphisms are common in UV-sensitive fair-skinned individuals and are associated with blunted cAMP second messenger signaling and higher lifetime risk of melanoma because of diminished ability of melanocytes to cope with UV damage. cAMP signaling p...

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Detaylı Bibliyografya
Yayımlandı:Exp Dermatol
Asıl Yazarlar: Wolf Horrell, Erin M., Jarrett, Stuart G., Carter, Katharine M., D’Orazio, John A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507718/
https://ncbi.nlm.nih.gov/pubmed/28094871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13291
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