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Investigation into the Biological Impact of Block Size on Cathepsin S-degradable HPMA Copolymers

N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers have been studied as an efficient carrier for drug delivery and tumor imaging. However, as with many macromolecular platforms, the substantial accumulation of HPMA copolymer by the mononuclear phagocyte system (MPS)-associated tissues, such as the...

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Bibliografiske detaljer
Udgivet i:Mol Pharm
Main Authors: Fan, Wei, Zhang, Wenting, Jia, Yinnong, Brusnahan, Susan K., Garrison, Jered C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507698/
https://ncbi.nlm.nih.gov/pubmed/28263073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b01038
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