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Investigation into the Biological Impact of Block Size on Cathepsin S-degradable HPMA Copolymers

N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers have been studied as an efficient carrier for drug delivery and tumor imaging. However, as with many macromolecular platforms, the substantial accumulation of HPMA copolymer by the mononuclear phagocyte system (MPS)-associated tissues, such as the...

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Bibliografische gegevens
Gepubliceerd in:Mol Pharm
Hoofdauteurs: Fan, Wei, Zhang, Wenting, Jia, Yinnong, Brusnahan, Susan K., Garrison, Jered C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507698/
https://ncbi.nlm.nih.gov/pubmed/28263073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b01038
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