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Investigation into the Biological Impact of Block Size on Cathepsin S-degradable HPMA Copolymers

N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers have been studied as an efficient carrier for drug delivery and tumor imaging. However, as with many macromolecular platforms, the substantial accumulation of HPMA copolymer by the mononuclear phagocyte system (MPS)-associated tissues, such as the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Pharm
Main Authors: Fan, Wei, Zhang, Wenting, Jia, Yinnong, Brusnahan, Susan K., Garrison, Jered C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507698/
https://ncbi.nlm.nih.gov/pubmed/28263073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b01038
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